90
Participants
Start Date
February 1, 2023
Primary Completion Date
October 31, 2026
Study Completion Date
October 31, 2026
Procedure: Usual Care (UC)
Intermittent spontaneous breathing periods
Procedure: UC + HI-IMT
UC + Supervised daily sessions of training including 4 sets of 6-10 full vital capacity breaths against an external load using a tapered flow resistive device (POWERbreathe KH2, HaB International, UK). The maximum tolerable resistance allowing patients to inhale at least 70% of their inspiratory vital capacity will be chosen and progressively increased throughout the training period.
Procedure: UC + LI-IMT (sham IMT)
UC + superrvised daily sessions of training including 4 sets of 6-10 breaths at the lowest external imposable load with the tapered flow resistive device (POWERbreathe KH2, HaB International, UK) (i.e. 3 cmH2O).
RECRUITING
University Hospital Leuven, Leuven
KU Leuven
OTHER