A 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

496

Participants

Timeline

Start Date

December 30, 2020

Primary Completion Date

September 6, 2024

Study Completion Date

September 6, 2024

Conditions
Early-stage Parkinson's Disease
Interventions
DRUG

UCB0599

Drug: UCB0599 Pharmaceutical form: Granules in capsules Route of administration: Oral use Participants will receive UCB0599 in a pre-specified sequence during the Treatment Period.

DRUG

Placebo

Drug: Placebo Pharmaceutical form: Capsules Route of administration: Oral use Participants will receive Placebo in a pre-specified sequence during the Treatment Period.

Trial Locations (115)

10021

Pd0053 50077, New York

10029

Pd0053 50521, New York

10032

Pd0053 50119, New York

11794

Pd0053 50530, Stony Brook

14221

Pd0053 50535, Williamsville

19107

Pd0053 50526, Philadelphia

21287

Pd0053 50547, Baltimore

22031

Pd0053 50410, Fairfax

22908

Pd0053 50542, Charlottesville

23456

Pd0053 50534, Virginia Beach

25827

Pd0053 50402, Crab Orchard

29425

Pd0053 50084, Charleston

33136

Pd0053 50199, Miami

33486

Pd0053 50396, Boca Raton

33613

Pd0053 50394, Tampa

34205

Pd0053 50524, Bradenton

35233

Pd0053 50140, Birmingham

37920

Pd0053 50532, Knoxville

38157

Pd0053 50543, Memphis

43210

Pd0053 50255, Columbus

43606

Pd0053 50527, Toledo

44106

Pd0053 50372, Cleveland

44195

Pd0053 50311, Cleveland

48334

Pd0053 50386, Farmington Hills

52242

Pd0053 50549, Iowa City

55130

Pd0053 50536, Saint Paul

60190

Pd0053 50399, Winfield

60611

Pd0053 50401, Chicago

66160

Pd0053 50074, Kansas City

70121

Pd0053 50395, New Orleans

72205

Pd0053 50539, Little Rock

74136

Pd0053 50398, Tulsa

77030

Pd0053 50113, Houston

78229

Pd0053 50400, San Antonio

80113

Pd0053 50531, Englewood

85013

Pd0053 50081, Phoenix

85710

Pd0053 50391, Tucson

89104

Pd0053 50397, Las Vegas

92037

Pd0053 50416, La Jolla

92708

Pd0053 50519, Fountain Valley

93710

Pd0053 50385, Fresno

97239

Pd0053 50510, Portland

99202

Pd0053 50419, Spokane

85004-1150

Pd0053 50506, Phoenix

90033-5315

Pd0053 50118, Los Angeles

06810

Pd0053 50392, Danbury

06030

Pd0053 50538, Farmington

30912-0004

Pd0053 50544, Augusta

60612-3863

Pd0053 50310, Chicago

40536-0284

Pd0053 50121, Lexington

21201-1606

Pd0053 50529, Baltimore

02114

Pd0053 50243, Boston

01655

Pd0053 50546, Worcester

08903

Pd0053 50299, New Brunswick

77030-5301

Pd0053 50525, Houston

05401-1473

Pd0053 50107, Burlington

98034-3030

Pd0053 50292, Kirkland

Unknown

Pd0053 50374, Calgary

Pd0053 50390, Kelowna

Pd0053 50387, Ottawa

Pd0053 50389, Toronto

Pd0053 40197, Amiens

Pd0053 40527, Bordeaux

Pd0053 40424, Créteil

Pd0053 40526, Lille

Pd0053 40130, Marseille

Pd0053 40635, Nantes

Pd0053 40524, Nîmes

Pd0053 40525, Paris

Pd0053 40131, Strasbourg

Pd0053 40528, Toulouse

Pd0053 40515, Berlin

Pd0053 40138, Bonn

Pd0053 40530, Dresden

Pd0053 40711, Erbach im Odenwald

Pd0053 40023, Erlangen

Pd0053 40710, Essen

Pd0053 40532, Haag in Oberbayern

Pd0053 40024, Hanover

Pd0053 40249, Kiel

Pd0053 40174, Mainz

Pd0053 40529, Marburg

Pd0053 40531, Regensburg

Pd0053 40555, Brescia

Pd0053 40533, Padua

Pd0053 40257, Roma

Pd0053 40534, Roma

Pd0053 40697, Roma

Pd0053 40359, Nijmegen

Pd0053 40694, Bydgoszcz

Pd0053 40719, Jelenia Góra

Pd0053 40539, Katowice

Pd0053 40538, Krakow

Pd0053 40696, Krakow

Pd0053 40700, Lodz

Pd0053 40702, Lublin

Pd0053 40535, Oświęcim

Pd0053 40536, Warsaw

Pd0053 40699, Warsaw

Pd0053 40705, Warsaw

Pd0053 40045, A Coruña

Pd0053 40159, Barcelona

Pd0053 40267, Barcelona

Pd0053 40046, Córdoba

Pd0053 40540, Madrid

Pd0053 40542, Móstoles

Pd0053 40352, Pamplona

Pd0053 40541, San Sebastián

Pd0053 40049, Seville

Pd0053 40175, London

Pd0053 40543, London

Pd0053 40698, London

Pd0053 40544, Motherwell

Pd0053 40306, Newcastle upon Tyne

Pd0053 40457, Plymouth

All Listed Sponsors
collaborator

The Parkinson Study Group

NETWORK

lead

UCB Biopharma SRL

INDUSTRY

NCT04658186 - A 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease | Biotech Hunter | Biotech Hunter