Cardiac Output Optimization on Postoperative Complications in Major Hepatic Surgery

NARecruitingINTERVENTIONAL
Enrollment

186

Participants

Timeline

Start Date

February 3, 2022

Primary Completion Date

March 15, 2026

Study Completion Date

May 15, 2026

Conditions
Primary or Metastatic Hepatic Adenocarcinoma
Interventions
BEHAVIORAL

Optimization of cardiac flow by base water-electrolyte supply

optimization of cardiac flow by base water-electrolyte supply of 1 ml / kg / h by Ringer Lactate® and faced with any decrease of more than 10% of the VES compared to the reference VES, achievement of an optimization of the preload by administration of 250 ml of Ringer Lactate® with renewal until correction of the VES.

BEHAVIORAL

Control arm

increase basic hydro-electrolyte supply of 6 ml / kg / h by Ringer Lactate® and 1: 1 blood loss compensation by crystalloids of the same nature.

Trial Locations (1)

13009

RECRUITING

Institut Paoli Calmettes, Marseille

All Listed Sponsors
lead

Institut Paoli-Calmettes

OTHER