NCT04653415View on ClinicalTrials.gov

Large Doses of Methylprednisolone Combined With Gabapentin in Total Knee Arthroplasty

PHASE4CompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

June 1, 2019

Primary Completion Date

January 1, 2020

Study Completion Date

May 1, 2020

Conditions
Arthroplasty ComplicationsKnee OsteoarthritisPain, PostoperativePerioperative Complication
Interventions
DRUG

Gabapentin 300mg

"The study group will receive as pre-emptive analgesia a single dose of 300 mg oral gabapentin and 125 mg intravenous methylprednisolone."

DRUG

Methylprednisolone 125 mg

"The study group will receive as pre-emptive analgesia a single dose of 300 mg oral gabapentin and 125 mg intravenous methylprednisolone."

DRUG

Tablet

The controls group will receive placebo orally - a tablet without any pharmacological properties, intravenously - normal saline solution

DRUG

Normal Saline 10 mL Injection

The controls group will receive placebo orally - a tablet without any pharmacological properties, intravenously - normal saline solution

Trial Locations (1)

30688

University Hospital in Krakow, Krakow

All Listed Sponsors
lead

Jagiellonian University

OTHER

NCT04653415 - Large Doses of Methylprednisolone Combined With Gabapentin in Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter