Evaluation of Lycopene in the Treatment of Erosive Oral Lichen Planus

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 1, 2018

Primary Completion Date

March 3, 2019

Study Completion Date

March 10, 2019

Conditions
Erosive Lichen Planus
Interventions
DRUG

Lycopene Softgel, 10 Mg

Patients were given 10 mg of lycopene softgel capsules once daily for two months. The active ingredient in each capsule consists of 10 mg lycopene from natural tomato extract.

DRUG

Prednisolone

Patients were given 40 mg of prednisolone tablets once daily in the morning for one month, afterwards, the dose was tapered along the following month. Incremental reduction of 10 mg each week for the first three weeks, followed by 5 mg reduction in the last week, was the tapering protocol in this study. The active ingredient in each tablet consists of Prednisolone metasulfobenzoate sodium 31.44 mg (equivalent to 20 mg of Prednisolone).

Trial Locations (1)

21512

Faculty of Dentistry, Alexandria University, Alexandria

All Listed Sponsors
collaborator

Alexandria University

OTHER

lead

Nourhan M.Aly

OTHER

NCT04652739 - Evaluation of Lycopene in the Treatment of Erosive Oral Lichen Planus | Biotech Hunter | Biotech Hunter