Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

July 31, 2026

Conditions
Kidney Stone
Interventions
DRUG

Potassium citrate

Slow release potassium citrate UroCit-K. Participants will take 20mEq twice daily.

DRUG

Sodium bicarbonate

650mg tabs. Take 3 tabs twice daily.

DIETARY_SUPPLEMENT

Litholyte

One packet is taken with 170ml of water. Two packets daily.

DIETARY_SUPPLEMENT

Crystal Lite

The classic lemonade contains 21.7mEq/liter of alkali Therefore, patients will take 2 litres daily to have the 40mEq of alkali daily needed.

DRUG

Potassium Bicarbonate

20 mEq tablets, one tablet twice daily

Trial Locations (1)

75390

University of Texas Southwestern Medical Center, Dallas

All Listed Sponsors
lead

University of Texas Southwestern Medical Center

OTHER