NCT04650841View on ClinicalTrials.gov

The Role of the Opioid System in Placebo Effects on Pain and Social Rejection

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

March 1, 2026

Study Completion Date

March 1, 2026

Conditions
PainRejectionPlacebo Effect
Interventions
DRUG

Placebo Cream with Naloxone

Participants will be informed that the spray is an effective pain and negative emotion reducing agent.

DRUG

Control Cream with Naloxone

Participants will be informed that the spray is saline.

DRUG

Placebo Cream with Saline

Participants will be informed that the spray is an effective pain and negative emotion reducing agent.

DRUG

Control Cream with Saline

Participants will be informed that the spray is saline.

Trial Locations (1)

03755

Dartmouth College, Hanover

All Listed Sponsors
lead

Trustees of Dartmouth College

OTHER