59
Participants
Start Date
December 3, 2020
Primary Completion Date
January 26, 2022
Study Completion Date
January 26, 2022
SARS-CoV-2 convalescent plasma
Participants will receive 200 ml convalescent plasma daily until SARS-CoV-2 is no longer detectable in the blood up to a maximum of 10 CP infusions. CP will be given as a slow infusion over 2 hours. CP neutralization titre of ≥ 1/640 or an ELISA reactivity against the Spike protein of SARS-CoV-2 by the Euroimmun commercial assay \>9 is desired. New antibody tests are under development and can be used instead if equivalence to neutralization or Euroimmun ELISA is demonstrated.
Standard of care
Standard of care as determined by hospital practices for COVID-19 patients.
Danderyd Hospital, Stockholm
Department of Infectious Disease, Falu Hospital, Falun
Department of Geriatrics, Karolinska University Hospital, Stockholm
Karolinska Institutet
OTHER
Danderyd Hospital
OTHER
Falu Hospital
OTHER
Joakim Dillner
OTHER