Randomized Study in Children and Adolescents With Migraine: Acute Treatment

PHASE3RecruitingINTERVENTIONAL
Enrollment

2,100

Participants

Timeline

Start Date

January 15, 2021

Primary Completion Date

January 9, 2029

Study Completion Date

January 9, 2029

Conditions
Pediatric Migraine
Interventions
DRUG

Rimegepant/BHV3000

BHV3000 (rimegepant) 75 mg or 50 mg ODT

DRUG

Matching placebo

Matching 75 mg or 50 mg ODT placebo

Trial Locations (242)

10003

RECRUITING

New York Neurology Associates, New York

10021

RECRUITING

Weill Cornell Medicine, New York

10029

ACTIVE_NOT_RECRUITING

Mount Sinai Hospital - Pharmacy Department, New York

10032

RECRUITING

Columbia University Medical Center Research Pharmacy, New York

RECRUITING

Columbia University Pediatric Neuromuscular Center, New York

RECRUITING

Irving Center for Clinical and Translational Research, Outpatient Clinical Research Unit, New York

RECRUITING

The Neurological Institute of New York, New York

RECRUITING

The Trustees of Columbia University and The New York and Presbyterian Hospital, New York

10456

TERMINATED

Prime Global Research, LLC, The Bronx

11042

RECRUITING

Northwell Health/ Division of Pediatric Neurology, Lake Success

11501

ACTIVE_NOT_RECRUITING

NYU Langone Hospital-Long Island, Clinical Research Center, Mineola

ACTIVE_NOT_RECRUITING

NYU Langone Hospital-Long Island, Pediatric Neurology, Mineola

11725

RECRUITING

True North Neurology, Commack

11776

ACTIVE_NOT_RECRUITING

North Suffolk Neurology P.C, Port Jefferson Station

14226

RECRUITING

Dent Neurosciences Research Center, Amherst

14618

TERMINATED

Finger Lakes Clinical Research, Rochester

19104

ACTIVE_NOT_RECRUITING

Children's Hospital of Philadelphia, Philadelphia

19803

ACTIVE_NOT_RECRUITING

Nemours Children's Hospital, Delaware, Wilmington

20010

RECRUITING

Children's National Medical Center, Washington D.C.

22222

RECRUITING

ProbarE i Lund AB, Lund

22902

RECRUITING

Pediatric Research of Charlottesville, LLC (Regulatory Only), Charlottesville

RECRUITING

Pediatric Research of Charlottesville, LLC, Charlottesville

23294

ACTIVE_NOT_RECRUITING

National Clinical Research, Inc., Richmond

23507

RECRUITING

Children's Hospital of the King's Daughters, Norfolk

RECRUITING

Children's Specialty Group, PLLC, Norfolk

23510

RECRUITING

Children's Specialty Group, PLLC, Division of Childhood & Adolescent Neurology, Norfolk

27405

RECRUITING

Headache Wellness Center, PC, Greensboro

27701

RECRUITING

Velocity Clinical Research, Inc., Durham

28036

ACTIVE_NOT_RECRUITING

Instituto de Investigaciones del Sueno, Madrid

28211

ACTIVE_NOT_RECRUITING

New Hope Clinical Research, Charlotte

28277

RECRUITING

OnSite Clinical Solutions, LLC, Charlotte

29605

ACTIVE_NOT_RECRUITING

Premier Neurology, PC, Greenville

29607

ACTIVE_NOT_RECRUITING

Tribe Clinical Research, LLC, Greenville

29615

ACTIVE_NOT_RECRUITING

Velocity Clinical Research - Greenville, Greenville

30030

RECRUITING

CenExel iResearch, LLC, Decatur

30329

RECRUITING

Children's Healthcare of Atlanta, Inc., Atlanta

RECRUITING

Childrens Healthcare of Atlanta, Atlanta

ACTIVE_NOT_RECRUITING

Rare Disease Research, LLC, Atlanta

31203

RECRUITING

Unidad de Investigacion en Salud de Chihuahua S.C., Chihuahua City

31520

RECRUITING

Pivotal Clinical Research & Associates, LLC, Brunswick

32055

ACTIVE_NOT_RECRUITING

Multi-Specialty Research Associates, Inc., Lake City

32073

RECRUITING

Coastal Clinical Research Specialists, Orange Park

32607

ACTIVE_NOT_RECRUITING

Sarkis Clinical Trials, Gainesville

32703

ACTIVE_NOT_RECRUITING

Topaz Clinical Research, Inc., Apopka

32720

TERMINATED

DeLand Clinical Research Unit, DeLand

32819

RECRUITING

Clinical Associates of Orlando, LLC, Orlando

33026

TERMINATED

Bioresearch Institute, Pembroke Pines

33126

RECRUITING

AppleMed Research Group, LLC, Miami

33134

ACTIVE_NOT_RECRUITING

Medical Research Center of Miami II, Inc, Miami

33155

NOT_YET_RECRUITING

Nicklaus Children's Hospital, Research Institute, Miami

33157

TERMINATED

Beautiful Minds Clinical Research Center, Cutler Bay

33166

RECRUITING

South Florida Research Phase I-IV, Inc, Miami Springs

33176

ACTIVE_NOT_RECRUITING

Brainstorm Research, Miami

33407

ACTIVE_NOT_RECRUITING

Premiere Research Institute at Palm Beach Neurology, West Palm Beach

33613

RECRUITING

Forcare Clinical Research, Tampa

33805

TERMINATED

Watson Clinic Center for Research, Inc., Lakeland

TERMINATED

Watson Clinic LLP, Lakeland

34102

ACTIVE_NOT_RECRUITING

Advanced Research for Health Improvement, LLC/ Dr. Cordero's Pediatric Office, Naples

34105

RECRUITING

Aqualane Clinical Research, Naples

35244

ACTIVE_NOT_RECRUITING

Achieve Clinical Research, LLC d/b/a Accel Research Sites-Neurology and Neurodiagnostic of Alabama, Birmingham

37203

ACTIVE_NOT_RECRUITING

Access Clinical Trials, Inc., Nashville

37660

ACTIVE_NOT_RECRUITING

Holston Medical Group., Kingsport

ACTIVE_NOT_RECRUITING

Holston Medical Group, Kingsport

38103

RECRUITING

Le Bonheur Children's Hospital - Outpatient Building, Memphis

RECRUITING

Le Bonheur Children's Hospital, Memphis

RECRUITING

Le Bonheur Childrens Hospital - Childrens Foundation Research Institute, Memphis

39008

ACTIVE_NOT_RECRUITING

Hospital Universitario Marqués de Valdecilla, Santander

39232

RECRUITING

Precise Research Centers, Flowood

40504

ACTIVE_NOT_RECRUITING

"Kentucky Neuroscience Institute Child Neurology-- Patients Seen", Lexington

40536

ACTIVE_NOT_RECRUITING

"UK Center for Clinical and Translational Science (CCTS) -- Patients Seen", Lexington

ACTIVE_NOT_RECRUITING

University of Kentucky Hospital, Lexington

41013

RECRUITING

Hospital Universitario Virgen del Rocío, Seville

43205

ACTIVE_NOT_RECRUITING

Nationwide Children's Hospital, Columbus

43228

ACTIVE_NOT_RECRUITING

Wellnow Urgent Care and Research, Columbus

44106

RECRUITING

University Hospitals Cleveland Medical Center, Cleveland

44308

RECRUITING

Akron Children's Hospital, Akron

44720

ACTIVE_NOT_RECRUITING

Neuro-Behavioral Clinical Research, Inc., North Canton

45229

RECRUITING

Cincinnati Children's Hospital Medical Center, Cincinnati

45242

RECRUITING

Velocity Clinical Research, Cincinnati

46074

RECRUITING

Options Research Group, LLC, Westfield

47005

RECRUITING

Hospital Clinico Universitario de Valladolid, Valladolid

48073

RECRUITING

Beaumont Hospital Royal Oak Campus, Royal Oak

48104

RECRUITING

Michigan Head Pain & Neurological Institute, Ann Arbor

49048

ACTIVE_NOT_RECRUITING

Wellnow Urgent Care and Research, Kalamazoo

49503

RECRUITING

Corewell Health, for and on behalf of Spectrum Health Hospital and Corewell Health Medical Group, Grand Rapids

RECRUITING

Corewell Health, Helen DeVos Children's Hospital, Grand Rapids

50265

RECRUITING

Integrated Clinical Trial Services, West Des Moines

51106

RECRUITING

Meridian Clinical Research, LLC, Sioux City

53144

RECRUITING

Clinical Investigation Specialists, Inc, Kenosha

53792

RECRUITING

University Hospital, Madison

59405

RECRUITING

Boeson Research, Great Falls

59804

RECRUITING

Blue Moose Pediatrics, Missoula

RECRUITING

Boeson Research Laboratory, Missoula

RECRUITING

Boeson Research, Missoula

59901

RECRUITING

Boeson Research, Kalispell

RECRUITING

Heart & Hands Midwifery, Kalispell

60563

RECRUITING

AMR-Baber Research Inc, Naperville

60657

RECRUITING

Chicago Headache Center & Research Institute, Chicago

65721

RECRUITING

Sharlin Health Neuroscience Research Center, Ozark

65810

ACTIVE_NOT_RECRUITING

Clinvest Research, LLC, Springfield

66212

ACTIVE_NOT_RECRUITING

College Park Family Care Center Physicians Group- Neurology Research Dept., Overland Park

66214

RECRUITING

Clinical Associates Midwest, LLC, Kansas City

68114

RECRUITING

Children's Hospital & Medical Center, Omaha

68526

TERMINATED

Alivation Research, LLC., Lincoln

70121

ACTIVE_NOT_RECRUITING

Ochsner Clinic Foundation, New Orleans

71105

ACTIVE_NOT_RECRUITING

Neurology and Headache Center, Inc., Shreveport

73106

ACTIVE_NOT_RECRUITING

IPS Research Company, Oklahoma City

74135

ACTIVE_NOT_RECRUITING

Lynn Institute of Tulsa, Tulsa

75034

ACTIVE_NOT_RECRUITING

North Texas Institute of Neurology and Headache, Frisco

75093

RECRUITING

AIM Trials, LLC, Plano

75201

RECRUITING

Infinite Research Group, LLC, Dallas

75235

RECRUITING

Children's Medical Center, Dallas, Dallas

RECRUITING

Children's Medical Center, Pediatric Anesthesiology Research (Study supplies only), Dallas

75251

RECRUITING

Cedar Health Research, Dallas

RECRUITING

FutureSearch Trials of Dallas, LLC, Dallas

75390

RECRUITING

The University of Texas Southwestern Medical Center, Dallas

77030

RECRUITING

UTHealth Houston, Houston

77054

RECRUITING

Pain and Headache Centers of Texas, Houston

77077

RECRUITING

SCLA Management, Houston

77081

ACTIVE_NOT_RECRUITING

Houston Clinical Research,LLC., Houston

77094

RECRUITING

NeuroCare Plus, Houston

77401

RECRUITING

Houston Clinical Trials, LLC, Bellaire

78723

RECRUITING

Dell Children's Medical Center, Austin

78749

RECRUITING

Child Neurology Consultants of Austin - South Austin, Austin

78757

RECRUITING

Child Neurology Consultants of Austin - Central Austin, Austin

78759

ACTIVE_NOT_RECRUITING

BioBehavioral Research of Austin, Austin

79912

RECRUITING

ANESC Research, El Paso

80045

RECRUITING

Children's Hospital Colorado- lnvestigational Drug Services, Aurora

RECRUITING

Children's Hospital Colorado, Aurora

80907

RECRUITING

Colorado Springs Neurological Associates, Colorado Springs

84107

RECRUITING

JBR Clinical Research, Salt Lake City

RECRUITING

Wasatch Clinical Research , LLC(Administrative Location), Salt Lake City

85253

RECRUITING

Perseverance Research Center, LLC, Scottsdale

85284

ACTIVE_NOT_RECRUITING

Physicians Research Group, Tempe

90057

ACTIVE_NOT_RECRUITING

National Research Institute, Los Angeles

90230

RECRUITING

ProScience Research Group, Culver City

90806

RECRUITING

Adult & Child Neurology Medical Associates, Long Beach

RECRUITING

Miller Children's & Women's Hospital Long Beach, Long Beach

91606

ACTIVE_NOT_RECRUITING

Velocity Clinical Research - North Hollywood, North Hollywood

91767

RECRUITING

The Neurology Group, Pomona

91786

RECRUITING

Pacific Clinical Research Management Group LLC, Upland

92037

RECRUITING

Altman Clinical and Translational Research Institute-IDS, La Jolla

RECRUITING

University of California, San Diego Altman Clinical Translational Research Institute, La Jolla

92408

RECRUITING

Velocity Clinical Research, San Bernardino (IP Delivery and Administering Location), San Bernardino

92627

RECRUITING

Adult & Child Neurology Medical Associates, Costa Mesa

92708

RECRUITING

Memorial Health Services, Fountain Valley

92805

RECRUITING

Advanced Research Center, Inc., Anaheim

92868

NOT_YET_RECRUITING

Children's Hospital of Orange County - Inpatient Pharmacy, Orange

NOT_YET_RECRUITING

Children's Hospital of Orange County - Neuroscience Center, Orange

NOT_YET_RECRUITING

Children's Hospital of Orange County, Orange

93710

RECRUITING

Neuro-Pain Medical Center, Fresno

94596

RECRUITING

Sunwise Clinical Research, Walnut Creek

95816

RECRUITING

University of California, Davis Midtown Clinic, Sacramento

95817

RECRUITING

UC Davis Medical Center, Investigational Drug Service (IDS) Pharmacy, Sacramento

RECRUITING

University of California, Davis Clinical and Translational Science Center Clinical Research (CCRC), Sacramento

97225

RECRUITING

Providence Brain & Spine Institute-research coordinator's office, Portland

RECRUITING

Providence Health & Services Investigational Drug Services Westside, Portland

RECRUITING

Providence Pediatric Neurology, Portland

97527

ACTIVE_NOT_RECRUITING

Velocity Clinical Research, Grants Pass, Grants Pass

98007

RECRUITING

Northwest Clinical Research Center, Bellevue

98105

RECRUITING

Seattle Children's Hospital Investigational Drug Services, Seattle

RECRUITING

Seattle Children's Hospital, Seattle

98201

ACTIVE_NOT_RECRUITING

Eastside Therapeutic Resource, Inc. dba Core Clinical Research, Everett

100089

RECRUITING

Chinese PLA General Hospital, Beijing

130021

RECRUITING

The First Hospital of Jilin University, Pediatric Neurology, Changchun

212001

RECRUITING

Affiliated Hospital of Jiangsu University, Zhenjiang

214023

RECRUITING

Wuxi Children's Hospital, Wuxi

214115

RECRUITING

Affiliated Hospital of Jiangnan University, Wuxi

215006

RECRUITING

The First Affiliated Hospital of Soochow University, Suzhou

221002

RECRUITING

Xuzhou Children's Hospital, Xuzhou

222002

RECRUITING

The Second People's Hospital of Lianyungang, Lianyungang

230000

RECRUITING

Anhui Provincial Hospital, Hefei

233000

RECRUITING

First Affiliated Hospital of Bengbu Medical College Neurology, Bengbu

250013

RECRUITING

Shandong Provincial Qianfoshan Hospital, Jinan

252000

RECRUITING

Liaocheng People's Hospital, Liaocheng

310052

RECRUITING

Children's Hospital of Zhejiang University School of Medicine, Hangzhou

315012

RECRUITING

Ningbo Women and Children's Hospital, Ningbo

325000

RECRUITING

The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou

400042

RECRUITING

" The First Affiliated Hospital of Chongqing Medical University", Chongqing

410000

RECRUITING

The Second Xiangya Hospital of Central South University, Changsha

410007

RECRUITING

Hunan Children's Hospital, Changsha

410013

RECRUITING

The Third Xiangya Hospital of Central South University, Changsha

430022

RECRUITING

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

430060

RECRUITING

Renmin Hospital of Wuhan University, Wuhan

434000

RECRUITING

Jingzhou First People's Hospital, Jingzhou

450000

RECRUITING

People's Hospital of Zhengzhou, Zhengzhou

518034

RECRUITING

Shenzhen Children's Hospital, Shenzhen

571140

RECRUITING

Hainan General Hospital, Haikou

610041

RECRUITING

West China Hospital of Sichuan University, Chengdu

710068

RECRUITING

Shaanxi Provincial People's Hospital, Xi'an

710075

RECRUITING

Xi'an Gaoxin Hospital Neurology Department, Xi'an

716000

RECRUITING

Yan 'an University Xianyang Hospital, Xianyang

730030

RECRUITING

Lanzhou university second hospital, Lanzhou

756000

RECRUITING

General Hospital of Ningxia Medical University, Yinchuan

800200

RECRUITING

Neurociencias Estudios Clinicos S.C., Culiacán

3760035

RECRUITING

Hikita Pediatric Clinic, Kiryu-shi

06416

RECRUITING

CT Clinical Research, Cromwell

06106

ACTIVE_NOT_RECRUITING

Connecticut Children's Medical Center, Hartford

06905

RECRUITING

Ki Health Partners, LLc, dba New England Institute for Clinical Research, Stamford

02131

ACTIVE_NOT_RECRUITING

Boston Clinical Trials, Boston

02451

ACTIVE_NOT_RECRUITING

MedVadis Research Corporation, Waltham

07753

NOT_YET_RECRUITING

HMH Jersey Shore University Medical Center, Neptune City

02818

RECRUITING

Velocity Clinical Research-Providence, East Greenwich

05401

RECRUITING

The University of Vermont Medical Center, Burlington

V1Y 1Z9

RECRUITING

OCT Research ULC, Kelowna

J1L 0H8

RECRUITING

Diex Recherche Sherbrooke Inc, Sherbrooke

G3K 2P8

NOT_YET_RECRUITING

Alpha Recherche Clinique, Québec

050000

RECRUITING

The First Hospital of Hebei Medical University, Shijiazhuang

050004

RECRUITING

The Second Hospital of Hebei Medical University, Shijiazhuang

Unknown

RECRUITING

Lu 'an People's Hospital, Lu'an

RECRUITING

Children's Hospital of Shanghai, Shanghai

RECRUITING

Shengjing Hospital of China Medical University, Shenyang

RECRUITING

The First Affiliated Hospital of Shihezi University School of Medicine, Shihezi

RECRUITING

Wuhan Children's Hospital, Wuhan

816-0802

RECRUITING

Jinnouchi Neurosurgical Clinic, Kasuga-shi

816-0824

RECRUITING

Ikeda Neurosurgical Clinic, Kasuga-shi

658-0064

RECRUITING

Konan Medical Center, Higashinada-ku Kobe-shi

663-8204

RECRUITING

Yamaguchi Clinic, Nishinomiya-shi

310-0015

RECRUITING

Mito Kyodo General Hospital, Mito

890-0052

RECRUITING

Tanaka Neurosurgery & Headache Clinic, Kagoshima

982-0014

RECRUITING

Sendai Headache and Neurology Clinic, Taihaku-ku Sendai-shi

545-0053

RECRUITING

Tennoji Dai Brain Clinic, Abeno-ku Osaka-shi

556-0015

RECRUITING

Tominaga Clinic, Naniwa-ku

338-8577

NOT_YET_RECRUITING

Saitama Neuropsychiatric Institute, Chuo-ku Saitama-shi

151-0051

RECRUITING

Tokyo Headache Clinic, Shibuya-ku

160-0023

NOT_YET_RECRUITING

Tokyo Medical University Hospital, Shinjuku-ku

730-8518

RECRUITING

Local lndependent Administrative Corporation Hiroshima City Hospital Organization Hiroshima City, Hiroshima

C.P. 06700.

RECRUITING

Clinstile S.A. de C.V., Col. Roma Norte

C.P. 54055

RECRUITING

Clinical Reseach Institute, S.C., Tlalnepantla

52-210

RECRUITING

MIGRE Polskie Centrum Leczenia Migreny Anna Gryglas-Dworak, Wroclaw

40-123

ACTIVE_NOT_RECRUITING

NZOZ Wielospecjalistyczna Poradnia Lekarska SYNAPSIS, Lech Szczechowski, Katowice

30-363

RECRUITING

Centrum Medyczne Plejady, Krakow

31-503

RECRUITING

Wojewódzki Specjalistyczny Szpital Dzieciecy im. Sw. Ludwika w Krakowie, Apteka Szpitalna, Krakow

61-731

RECRUITING

Clinical Research Center Sp. z.o.o. Medic-R Spolka komandytowa, Poznan

70-111

ACTIVE_NOT_RECRUITING

Euromedis Sp. z o. o., Szczecin

08035

RECRUITING

Hospital Universitario Vall d'Hebron, Barcelona

08550

ACTIVE_NOT_RECRUITING

Centre d'Atencio Primaria Balenya, Barcelona

703 62

ACTIVE_NOT_RECRUITING

Avdelningen för kliniska Prövningar, Universitetssjukhuset Örebro, Örebro

113 29

RECRUITING

ProbarE i Stockholm AB, Stockholm

LE1 5WW

ACTIVE_NOT_RECRUITING

Leicester Royal Infirmary, Leicester

W1G 9JF

RECRUITING

Re:Cognition Health Limited, London

WC1N 3JH

RECRUITING

Great Ormond Street Hospital for Children NHS Foundation Trust, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT04649242 - Randomized Study in Children and Adolescents With Migraine: Acute Treatment | Biotech Hunter | Biotech Hunter