SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

PHASE4RecruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

June 28, 2021

Primary Completion Date

September 30, 2026

Study Completion Date

March 31, 2027

Conditions
Hemophilia A With InhibitorHemophilia B With Inhibitor
Interventions
DRUG

coagulation factor VIIa [recombinant]-jncw

a transgenically produced, activated, recombinant, human factor VII (rhFVIIa) protein with the brand name of SEVENFACT®. This protein is a clotting factor in the coagulation cascade that is produced in and purified from the milk of transgenic rabbits. SEVENFACT is approved for the treatment and control of bleeding episodes occurring in adults and adolescents (12 years of age and older) with hemophilia A or B with inhibitors.

Trial Locations (22)

11040

RECRUITING

Northwell Health, Long Island Jewish, New Hyde Park

20010

RECRUITING

Children's National Hemophilia Center, Washington D.C.

27834

NOT_YET_RECRUITING

Brody School of Medicine at East Carolina University, Greenville

31404

RECRUITING

Hemophilia of Georgia Center for Bleeding and Clotting Disorders of Emory, Adult Division, Atlanta

RECRUITING

Willett Children's Hospital at Memorial University Medical Center, Savannah

32806

COMPLETED

Arnold Palmer Hospital for Children - The Haley Center for Children's Cancer and Blood Disorders, Orlando

37212

RECRUITING

Vanderbilt University Medical Center, Nashville

44106

RECRUITING

University Hospitals Health System Cleveland, Cleveland

48201

RECRUITING

Children's Hospital of Michigan, Detroit

48202

RECRUITING

Henry Ford Health System, Detroit

48912

RECRUITING

MSU Center for Bleeding and Clotting Disorders, Lansing

55455

NOT_YET_RECRUITING

Center for Bleeding and Clotting Disorders, University of Minnesota, Minneapolis

55905

RECRUITING

Mayo Comprehensive Hemophilia Center, Rochester

64108

RECRUITING

Kansas City Regional Hemophilia Center, Kansas City

70112

WITHDRAWN

Louisiana Center for Bleeding and Clotting Disorders, Tulane, New Orleans

72202

RECRUITING

Arkansas Center for Bleeding Disorders, Little Rock

73104

RECRUITING

Oklahoma Center for Bleeding and Clotting Disorders, Oklahoma City

77030

RECRUITING

Gulf States Hemophilia and Thrombophilia Center-University of Texas Health Science Center @Houston, Houston

85016

COMPLETED

Arizona Hemophilia and Thrombosis Center at Phoenix Children's Hospital, Phoenix

90007

RECRUITING

Orthopaedic Institute for Children, Los Angeles

95817

RECRUITING

University of California at Davis UC Davis Hemostasis and Thrombosis Center, Sacramento

02114

RECRUITING

Massachusetts General Hospital Comprehensive Hemophilia and Thrombosis Treatment Center, Boston

All Listed Sponsors
lead

American Thrombosis and Hemostasis Network

NETWORK

collaborator

LFB USA, Inc.

INDUSTRY