Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile Surgery

NAEnrolling by invitationINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

June 1, 2019

Primary Completion Date

June 1, 2020

Study Completion Date

June 1, 2025

Conditions
Macular Corneal Dystrophy
Interventions
PROCEDURE

Fresh Corneal Lenticule Implantation using Relex-Smile Surgery

Knowing that the most important element is damage of stroma we used all preoperative procedures atlas, optic tomography and especially electron microscope. Approximately we planned how much microns we remove and insert, for example we remove 80 µm and we insert fresh corneal lenticule 90 µm with the purpose to remove more dead keratocytes which increase biomechanical instability of corneal metabolism (abnormal increase collagenase activity, decrease proteinase inhibitors, excessive premature keratocyte apoptosis, increase cytokine binding). Fresh Corneal Lenticule and autologous serum contains live stem cells that produce keratocytes, collagen fibers, extracellular matrix which contribute to the regeneration of the cornea, and all this results at increasing of corneal transparency and visual acuity in patients with corneal macular dystrophy.

Trial Locations (1)

10000

Eye Hospital Pristina, Pristina

All Listed Sponsors
lead

Eye Hospital Pristina Kosovo

OTHER