Apatinib Plus Camrelizumab in Patients With Previously Treated Advanced Biliary Tract Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

December 1, 2018

Primary Completion Date

December 1, 2020

Study Completion Date

January 1, 2021

Conditions
Biliary Tract CancerCholangiocarcinomaBiomarkerHepatobiliary Neoplasm
Interventions
DRUG

Apatinib plus Camrelizumab

Patients received apatinib orally at 250 mg once a day irrespective of the patient weight. During the treatment, apatinib can reduced to half of piece or once every other day considering the grade of treatment related adverse events. Camrelizumab 200 mg was administered intravenously over 30 minutes every 3 weeks. The intermittent period of camrelizumab was no longer than 6 weeks. All patients continued combination treatment until disease progression, unacceptable toxicity, or discontinuation for any reason.

Trial Locations (2)

100730

Chinese Academy of Medical Sciences & Peking Union Medical College Hospital (CAMS&PUMCH), Beijing

Hai-Tao Zhao, Beijing

All Listed Sponsors
lead

Peking Union Medical College Hospital

OTHER

NCT04642664 - Apatinib Plus Camrelizumab in Patients With Previously Treated Advanced Biliary Tract Cancer | Biotech Hunter | Biotech Hunter