Dexmedetomidine as an Adjuvant for Femoral Nerve Block and Functional Recovery After Total Knee Arthroplasty

PHASE4CompletedINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

November 25, 2020

Primary Completion Date

November 22, 2021

Study Completion Date

February 25, 2022

Conditions
ElderlyTotal Knee ArthroplastyFemoral Nerve BlockDexmedetomidineFunctional Outcome
Interventions
DRUG

Dexmedetomidine

Patients in the dexmedetomidine group receive single-shot femoral nerve block preoperatively using a mixture of 0.375% ropivacaine and 1.0 μg/kg dexmedetomidine, in a total volume of 20 ml.

DRUG

Placebo

Patients in the control group receive single-shot femoral nerve block preoperatively using a mixture of 0.375% ropivacaine and normal saline, in a total volume of 20 ml.

Trial Locations (2)

100034

Peking University First Hospital, Beijing

100035

Beijing Jishuitan Hospital, Beijing

All Listed Sponsors
collaborator

Beijing Jishuitan Hospital

OTHER

lead

Peking University First Hospital

OTHER

NCT04642651 - Dexmedetomidine as an Adjuvant for Femoral Nerve Block and Functional Recovery After Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter