Proton Pump Inhibitors (PPI): a Study to Improve Appropriate Prescriptions in the Elderly

NACompletedINTERVENTIONAL
Enrollment

800

Participants

Timeline

Start Date

October 10, 2019

Primary Completion Date

March 14, 2023

Study Completion Date

March 14, 2024

Conditions
Proton Pump InhibitorPrimary Care
Interventions
BEHAVIORAL

Educational intervention

The GPs randomized to the intervention arm will receive a feedback informing on their absolute number of patients treated with at least one PPI during the baseline period and if they have been prescribed above or below the median of appropriate prescriptions rate in their local area. They will be also provided with a scientific document including technical details on AIFA reimbursement criteria (NOTA 1 and 48), short hints about adverse events related to PPI long- term use in older patients and recommendation on how to discontinue PPI therapy (i.e. gradual step down administration to avoid paradoxical effect).

Trial Locations (3)

20099

IRCCS MultiMedica- MultiMedica Spa, Sesto San Giovanni

20156

Mario Negri Institute for Pharmacological Research, Milan

80131

Università degli studi di Napoli Federico II, Napoli

All Listed Sponsors
collaborator

IRCCS Multimedica

OTHER

collaborator

Federico II University

OTHER

lead

Mario Negri Institute for Pharmacological Research

OTHER

NCT04637750 - Proton Pump Inhibitors (PPI): a Study to Improve Appropriate Prescriptions in the Elderly | Biotech Hunter | Biotech Hunter