517
Participants
Start Date
November 23, 2020
Primary Completion Date
August 22, 2022
Study Completion Date
October 24, 2023
Trastuzumab
Trastuzumab IV infusion in 3-week cycles. Neoadjuvant treatment: 8 milligrams per kilogram (mg/kg) loading dose for Cycle 1, followed by 6 mg/kg for Cycles 2-4.
QL1209
QL1209 IV infusion in 3-week cycles. Prior to surgery (neoadjuvant treatment): 840 milligrams (mg) loading dose for Cycle 1, followed by 420 mg for Cycles 2-4.
Pertuzumab
Pertuzumab IV infusion in 3-week cycles. Prior to surgery (neoadjuvant treatment): 840 milligrams (mg) loading dose for Cycle 1, followed by 420 mg for Cycles 2-4.
Docetaxel
Docetaxel IV infusion in 3-week cycles. Neoadjuvant treatment: 75 mg/m2 for Cycles 1-4
surgery
All participants who are eligible for surgery will undergo surgery and have their pathologic response evaluated.
Tianjin Medical University Cancer Institution & Hospital, Tianjin
Fudan University Cancer Hospital, Shanghai
Qilu Pharmaceutical Co., Ltd.
INDUSTRY