Effect of Neuroplasticity Modulation in tDCS Treatment Response Among Schizophrenia Patients With Auditory Hallucination

NARecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

April 2, 2024

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
SchizophreniaSchizoaffective Disorder
Interventions
DEVICE

Verum Accelerated Transcranial Direct Current Stimulation (acctDCS)

In verum transcranial direct current stimulation (tDCS), patient will receive five sessions daily for two days, a 10-session course of tDCS \[anode: left-DLPFC (at F3) and cathode: left-TPJ (midway between C3 and P3); electrode size: 35cm2\]. For Verum-tDCS condition, 2-mA of constant current will be delivered for 20-minutes, additional ramp-up and ramp-down of 20 seconds each.

DEVICE

Sham Accelerated Transcranial Direct Current Stimulation (acctDCS)

In sham transcranial direct current stimulation (tDCS), each SCZ patient will receive five sessions daily for two days, a 10-session course of tDCS \[anode: left-DLPFC (at F3) and cathode: left-TPJ (midway between C3 and P3); electrode size: 35cm2\]. However, no current will be delivered beyond initial ramp-up time though the tDCS device display will indicate that 2mA current is being applied.

Trial Locations (1)

560029

RECRUITING

Department of Psychiatry, National Institute of Mental Health And Neuro Sciences (NIMHANS), Bengaluru, Karnataka, Bengaluru

All Listed Sponsors
lead

National Institute of Mental Health and Neuro Sciences, India

OTHER