Corneal Nerves After Treatment With Cenegermin

CompletedOBSERVATIONAL
Enrollment

8

Participants

Timeline

Start Date

May 23, 2022

Primary Completion Date

March 25, 2025

Study Completion Date

March 25, 2025

Conditions
Neurotrophic Keratitis
Interventions
DRUG

Cenegermin Ophthalmic Solution [Oxervate]

An 8-week course of topical cenegermin eye drops given 6 times daily would be started in the affected eye, in conjunction with the pre-existing medical treatment for neurotrophic keratopathy. Patients will be followed-up at 4 weeks, 6 weeks, 8 weeks, 3 months, 6 months, 9 months and 12 months (±2 weeks at each time point) after treatment. At each visit, patients will be assessed to determine the corneal epithelial defect and corneal sensation.

Trial Locations (1)

90095

University of California, Los Angeles, Los Angeles

All Listed Sponsors
collaborator

Dompé Farmaceutici S.p.A

INDUSTRY

lead

University of California, Los Angeles

OTHER