Neoadjuvant Therapy for Locally Advanced Colon Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

January 4, 2021

Primary Completion Date

September 30, 2023

Study Completion Date

September 30, 2023

Conditions
Colon CancerNeoadjuvant Therapy
Interventions
DRUG

Camrelizumab , apatinib and chemotherapy

"Camrelizumab 200 mg, IV infusion on Days 1 each 14-day cycle~Apatinib 250mg oral administration once a day, for two months~mFOLFOX6 oxaliplatin 85 mg/m\^2 IV infusion on Day 1 of each14-day cycle. Fluorouracil: 400 mg/m2 as a bolus injection given after a two-hour leucovorin infusion at a dose of 400 mg/m2. The loading dose is then followed by a 46-hour 5-fluorouracil infusion of 2,400 mg/m2 via a pump programmed to provide a constant drug infusion rate."

Trial Locations (1)

310006

First affiliated hospital, Zhejiang University, Hangzhou

All Listed Sponsors
lead

Zhejiang University

OTHER

NCT04625803 - Neoadjuvant Therapy for Locally Advanced Colon Cancer | Biotech Hunter | Biotech Hunter