Protection of Cardiac Function With Left Bundle Branch Pacing in Patients With Atrioventricular Block

NAActive, not recruitingINTERVENTIONAL
Enrollment

683

Participants

Timeline

Start Date

June 22, 2021

Primary Completion Date

June 30, 2028

Study Completion Date

June 30, 2028

Conditions
Atrioventricular Block
Interventions
PROCEDURE

Left bundle branch pacing

"LBBP is defined if fulfilling criterion 1 and at least one in criteria 2:~1. Paced morphology of RBBD in surface lead V1 (QR, Qr, rSr', rSR' or Qrs);~2. One of the following should be met:~ 1. Selective LBBP with an iso-electrical window between the pacing spike and QRS onset;~ 2. If using dual-lead method with one at His-bundle and the other at LBB region, a retrograde His-bundle potential is recorded from His-bundle lead during LBBP;~ 3. LVATs at lead tip pacing of 1.5V/0.5ms and 10V/0.5ms are ≤ 80ms and the difference is \< 10ms;~ 4. A discrete LBB potential is recorded from lead tip and LVAT at tip pacing of 3V/0.5ms is ≤ 80ms19.~If criterion 1 is fulfilled but none in criteria 2 is met, the procedure is considered to be left ventricular septal pacing (LVSP)."

PROCEDURE

Right ventricular pacing

Implantation of a RV pacing lead is attempted using the standard-of-care technique first.

Trial Locations (1)

210029

The First Affiliated Hospital with Nanjing Medical University, Nanjing

All Listed Sponsors
collaborator

West China Hospital

OTHER

collaborator

First Affiliated Hospital of Wenzhou Medical University

OTHER

collaborator

Shanghai Zhongshan Hospital

OTHER

collaborator

Zhongshan Hospital Xiamen University

OTHER

collaborator

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

collaborator

Fujian Medical University Union Hospital

OTHER

collaborator

Xijing Hospital

OTHER

collaborator

First Affiliated Hospital Xi'an Jiaotong University

OTHER

collaborator

Southwest Hospital, China

OTHER

collaborator

Beijing Chao Yang Hospital

OTHER

lead

The First Affiliated Hospital with Nanjing Medical University

OTHER