Complex Phytoadaptogenes in Chronic Periodontitis Treatment.

PHASE4CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

February 1, 2019

Primary Completion Date

May 1, 2019

Study Completion Date

November 1, 2019

Conditions
Chronic Periodontitis
Interventions
DRUG

Cocktail from complex phytoadaptogens (CFA)

Cocktail from complex phytoadaptogens (CFA) is composed from 70% alcohol extracts of Glycyrrhiza glabra, Rhodiola rosea, Acantopanax senticosus in the ratio 2:1:1. Application of CFA in 3 group was carried out after non-surgical periodontal therapy (NSPT). After NSPT the patient filled out an Estberg questionnaire to determine the chronotype. After processing the questionnaire, a chronotype was identified and the patient was prescribed CFA dosage. Application of CFA was carried out in the periods of exacerbation of chronic periodontitis within 28 days with a dosage of CFA depending on the chronotype of the person - morning chronotype at 45 drops in the morning before 10.00 o'clock; independent chronotype 20 drops 3 times a day; evening chronotype 30 drops at 14.00 o'clock and 20 drops at 19.00 o'clock.

PROCEDURE

Standard non-surgical periodontal treatment (NSPT)

Oral hygiene instructions (including brushing technique, the use of interdentally flosses, and/or brushes), NSPT (mouth scaling and root planing using an ultrasonic scaler UDS-L LED (Woodpecker, China) and Graceys curettes (Hu Friedy, Chicago, USA)). The treated periodontal pockets were irrigated with 0.12% chlorhexidine gluconate. Patients were given recommendation to rinse their mouth three times daily for 14 days using 0.12% chlorhexidine gluconate

Trial Locations (1)

362025

1Institute of Biomedical Investigations - the Affiliate of Vladikavkaz Scientific Centre of Russian Academy of Sciences, Vladikavkaz

All Listed Sponsors
lead

Vladikavkaz Scientific Center of the Russian Academy of Sciences

NETWORK

NCT04623164 - Complex Phytoadaptogenes in Chronic Periodontitis Treatment. | Biotech Hunter | Biotech Hunter