Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction

PHASE3CompletedINTERVENTIONAL
Enrollment

321

Participants

Timeline

Start Date

February 22, 2020

Primary Completion Date

October 12, 2022

Study Completion Date

October 20, 2022

Conditions
Acute Pain
Interventions
COMBINATION_PRODUCT

nefopam hydrochloride 30mg / paracetamol 500mg X2

The first intake is taken right after randomization. Then on-demand period (5 days maximum) respecting a 6-hour interval between intakes, and up to 3 intakes per day.

DRUG

Paracetamol 500 Mg Oral Tablet X2

The first intake is taken right after randomization. Then on-demand period (5 days maximum) respecting a 6-hour interval between intakes, and up to 3 intakes per day.

DRUG

Nefopam HCl 30 MG Oral Tablet X2

The first intake is taken right after randomization. Then on-demand period (5 days maximum) respecting a 6-hour interval between intakes, and up to 3 intakes per day.

Trial Locations (19)

13385

CHU Marseille, Marseille

37170

CHU de tours, Tours

49933

CHU Angers, Angers

83800

HIA Toulon, Toulon

95300

Centre Hospitalier de Pontoise, Pontoise

141207

LLC Center for interdisciplinary dentistry & neuro, Moscow

150062

Regional clinical hospital, Yaroslavl

Unknown

Hôpital Leuven, Leuven

Clinexpert Kft., Budapest

Óbudai Egészségügyi Centrum, Budapest

Swan-Med Kft., Létavértes

Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókórház,, Nyíregyháza

Szent Borbála Kórház,, Tatabánya

Óbudai Egészségügyi Centrum, Zalaegerszeg

State Medico-stomato Univ., by A.I. Evdokimov, Moscow

B5 7EG

Birmingham School of Dentistry, Birmingham

CF14 4XY

University Dental Hospital, Cardiff

EH3 9HX

Edinburgh Dental Institute, Edinburgh

E1 1FR

BARTS HEALTH NHS TRUST Royal London Hospital, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Excelya

INDUSTRY

lead

Unither Pharmaceuticals, France

INDUSTRY

NCT04622735 - Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction | Biotech Hunter | Biotech Hunter