A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation

PHASE3CompletedINTERVENTIONAL
Enrollment

135

Participants

Timeline

Start Date

December 8, 2020

Primary Completion Date

June 2, 2021

Study Completion Date

August 17, 2021

Conditions
Sedation in Intensive Care
Interventions
DRUG

HSK3486

Loading Dose:0.1 mg/kg, infused with 4 min ± 30 s; Maintenance Dose:Maintenance is started at 0.3 mg/kg/h, and the dose can be adjusted up and down by 0.05-0.1 mg/kg/h. Range of maintenance dose: 0.06-0.8 mg/kg/h

DRUG

Propofol

"Loading Dose:0.5 mg/kg, infused with 4 min ± 30 s~Maintenance Dose:Maintenance is started at 1.5 mg/kg/h, and the dose can be adjusted up and down by 0.25-0.5 mg/kg/h. Range of maintenance dose:~0.3-4 mg/kg/h"

Trial Locations (1)

Unknown

The First Affiliated Hospital of Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

Haisco Pharmaceutical Group Co., Ltd.

INDUSTRY

NCT04620031 - A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation | Biotech Hunter | Biotech Hunter