Combined Air-plasma Flow and Nitric Oxide Therapy in Cardiac Surgery

NACompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

March 14, 2017

Primary Completion Date

December 20, 2021

Study Completion Date

December 20, 2023

Conditions
Mediastinitis
Interventions
PROCEDURE

NO-based treatment of sterno-mediastinitis

"Preparation of a postoperative wound in case of infectious complications. A mandatory sampling material for culture and antibiotic sensitivity is collected before and after the air plasma flow treatment.~Direct effect of the air-plasma flow on the entire wound surface in sterilization mode with an exposure of 2-3 minutes for each surgical wound, until the level of bacterial contamination decreases to 10-5 and below.~The technique of using air-plasma flow when closing a wound after preventing infectious complications in it.~In the postoperative period, daily air-plasma flow treatment in sterilization mode along the suture line for 3 minutes. Penetrating drainage NO supply in the biological stimulation mode daily for 10 days, with an exposure of 1-2 minutes up to 10 days, with a volume of up to 2 liters per minute.~Collecting wound culture from the drainage containers on 1-3-7-12 days to detect pathogens and the bacterial number."

PROCEDURE

Treatment of sterno-mediastinitis

patients who were treated for sterno-mediastinitis according to clinical guidelines, the main method of which is a permanent irrigation and aspiration flow drainage method, as well as a Vacuum Assisted Closure (VAC) system of dressings for vacuum drainage

Trial Locations (1)

634012

TomskNRMC, Tomsk

All Listed Sponsors
lead

Tomsk National Research Medical Center of the Russian Academy of Sciences

OTHER

NCT04617353 - Combined Air-plasma Flow and Nitric Oxide Therapy in Cardiac Surgery | Biotech Hunter | Biotech Hunter