5500/20 Vs. SABR or Brachytherapy for PRimary OligoMetastatic Prostate Cancer Treatment (PROMPT)

NARecruitingINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

July 12, 2021

Primary Completion Date

June 30, 2030

Study Completion Date

June 30, 2033

Conditions
Oligometastatic Prostate Cancer
Interventions
RADIATION

Hypofractionated external beam radiotherapy

5500 cGy/20 fractions delivered 5 days per week over 4 weeks

RADIATION

High dose rate brachytherapy

A single fraction of 19 Gy is delivered from an automated afterloading Iridium-192 source via interstitial catheters placed under ultrasound guidance

RADIATION

Permanent seed implant

Iodine-125 radioactive seeds are implanted permanently in the prostate in a single procedure under transrectal ultrasound guidance

RADIATION

Stereotactic body radiotherapy

External radiation using SABR technology delivers 36.25 Gy to the prostate in 5 fractions given either once weekly for 5 weeks or every second day over 2 weeks.

Trial Locations (4)

V1Y5L3

RECRUITING

British Columbia Cancer Agency Center for the Southern Interior, Kelowna

Unknown

NOT_YET_RECRUITING

Fraser Valley Cancer Center, Surrey

NOT_YET_RECRUITING

Vancouver Cancer Center, Vancouver

RECRUITING

Vancouver Island Cancer Center, Victoria

All Listed Sponsors
lead

British Columbia Cancer Agency

OTHER