Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Hospitalized Patients

"Treatment involves escalating doses to the target dose of 14 mg / day~1. / Dose escalation:~ * Level 1: 3.5 mg/day (1/2 patch) for 2 days (D1 and D2)~ * Level 2: 7 mg/day (1 patch) for 2 days (D3 and D4)~ * Level 3: 10.5 mg/day (1.5 patch) for 2 days (D5 and D6)~ * Level 4: target dose = 14 mg/day (from D7 to discharge from hospital + 1 week or maximum 5 weeks after the start of treatment)~2. / Decrease in dose (1 week after exit from hospital or maximum 5 weeks after the start of treatment): Decrease of 3.5 mg (1/2 patch) per week (over 3 weeks maximum)"

Placebo of nicotine patch administered to the same administration schedule as in the experimental arm