PRONing to Facilitate Weaning From ECMO in Patients With Refractory Acute Respiratory Distress Syndrome

NACompletedINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

March 3, 2021

Primary Completion Date

March 7, 2022

Study Completion Date

December 31, 2022

Conditions
ARDS
Interventions
PROCEDURE

Prone positionning

4 to 5 persons required for the procedure, one of them being dedicated to the management of the head of the patient, the endotracheal tube, the jugular ECMO cannula and the ventilator lines and another dedicated to the femoral ECMO cannula. The person at the head of the bed will coordinate the steps. The other persons will stand at each side of the bed. The direction of the rotation will be decided giving priority to the side of the central venous lines. The length of vascular and ventilator lines will be checked for appropriateness, the endotracheal tube and gastric tube will be secured, and the patient's knees, forehead, chest, and iliac crests will be protected using adhesive pads. The patient will be then moved along the horizontal plane to the opposite side of the bed selected for the direction of rotation. Patients will be proned at least four times during the first days on ECMO. Each prone session will stand for at least 16 hours

PROCEDURE

Supine position

Patients assigned to supine will remain in a semi-recumbent position.

Trial Locations (1)

75013

Hôpital Pitié Salpêtrière, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT04607551 - PRONing to Facilitate Weaning From ECMO in Patients With Refractory Acute Respiratory Distress Syndrome | Biotech Hunter | Biotech Hunter