Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy

PHASE4CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 21, 2020

Primary Completion Date

January 20, 2021

Study Completion Date

January 26, 2021

Conditions
Hemodynamic InstabilitySupratentorial Neoplasms
Interventions
DRUG

Dexmedetomidine

"On the scheduled time of operation, the head nurse opened each envelope just before surgery, prepared the infusion solution and handled it to the anesthesiologist who was blinded to the solution. He was then determined for collecting perioperative data.~Group D: Patients received 0.5 µg/kg/h of Dexmedetomidine. Dexmedetomidine dosage was diluted in 50 ml syringe of normal saline Group C: Patients received equal volume and rate of normal saline as Group D.~This dosing regimen was in accordance with existing guidelines \[5\] \[6\] \[7\]."

DRUG

normal saline

"On the scheduled time of operation, the head nurse opened each envelope just before surgery, prepared the infusion solution and handled it to the anesthesiologist who was blinded to the solution. He was then determined for collecting perioperative data.~Group C: Patients received equal volume and rate of normal saline as Group D."

Trial Locations (1)

Unknown

Ain Shams University Hospitals, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT04607525 - Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy | Biotech Hunter | Biotech Hunter