Voluntary Activation During Isokinetic Contractions in Subjects with Neuromotor Disorders

NARecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 7, 2020

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Multiple SclerosisPoststroke/CVA HemiparesisParkinson DiseaseKnee Impairment
Interventions
OTHER

Pathologic group

"Voluntary Activation level will be determined according to the interpolate twitch technique (ITT).~During isometric contractions (knee at 40° flexion), three electric shocks (doublets) will be delivered. The first shock will be delivered at rest before contraction. The second one will be delivered 3-4 s after the beginning of the effort. The third one will be delivered at rest 2-3 s after the contraction has ended. Two isometric contractions will be performed, with a 3-minute break.~Then, 3 consecutive continuous passive motion (CPM) extension-flexions of the knee joint (range 105-0°), and 3 isokinetic concentric contractions (ISOK) will be performed. During both CPM and ISOK an electric shock will be delivered during each repetition. The instant of stimulation will be determined in a way allowing the twitch moments to peak at exactly 40° of knee flexion during extension. The same procedure will be administered first to the affected limb, and then to the non-affected limb."

Trial Locations (1)

20121

RECRUITING

Istituto Auxologico Italiano, Milan

All Listed Sponsors
lead

Istituto Auxologico Italiano

OTHER