NCT04606186View on ClinicalTrials.gov

Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment in Adult Patients

NAUnknownINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

October 19, 2020

Primary Completion Date

November 1, 2023

Study Completion Date

November 1, 2023

Conditions
GingivitisPeriodontal InflammationOrthodontic Appliance Complication
Interventions
DIETARY_SUPPLEMENT

Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289)

Supplementary intake of Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289) 2 times per day for 12 weeks

DIETARY_SUPPLEMENT

Placebo-lozenges (BioGaia)

Placebo-lozenges (BioGaia)

Trial Locations (1)

91054

RECRUITING

Department of Orthodontics and Orofacial Orthopedics, Erlangen

Sponsors

Collaborators (1)

BioGaia AB
All Listed Sponsors
collaborator

BioGaia AB

INDUSTRY

lead

University of Erlangen-Nürnberg

OTHER

NCT04606186 - Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment in Adult Patients | Biotech Hunter | Biotech Hunter