Levels of Matrix Metalloproteinase-8 After Intrapocket Treatment in Moderate Periodontitis Patients.

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 13, 2020

Primary Completion Date

August 31, 2020

Study Completion Date

October 14, 2020

Conditions
Periodontitis
Interventions
DRUG

lemongrass essential oil gel

"The lemongrass oil gel will be administered by means of a syringe with a bent, blunt-end needle. The needle will be carefully inserted into the periodontal pocket and the gel will be applied in the test sites in a gentle probing manner, attempting to fill the full extent of the pocket. The gel will be applied up to the gingival margin and the excess gel will be removed with sterile gauze.~Periodontal dressing will be applied after the delivery of the drug, and they will be also asked not to eat for thirty minutes.~After placement of the gel in situ, patients will be instructed to follow strict oral hygiene protocol and not chew hard or sticky foods at the gel placement sites for rest of the week."

DRUG

Placebo

"The placebo will be administered by means of a syringe with a bent, blunt-end needle. The needle will be carefully inserted into the periodontal pocket and the gel will be applied in the test sites in a gentle probing manner, attempting to fill the full extent of the pocket. The gel will be applied up to the gingival margin and the excess gel will be removed with sterile gauze.~Periodontal dressing will be applied after the delivery of the drug, and they will be also asked not to eat for thirty minutes.~After placement of the gel in situ, patients will be instructed to follow strict oral hygiene protocol and not chew hard or sticky foods at the gel placement sites for rest of the week."

PROCEDURE

Scaling and root planing

Conventional mechanical treatment by ultra-sonic scalers

Trial Locations (1)

Unknown

Alexandria University, Alexandria

All Listed Sponsors
lead

Alexandria University

OTHER

NCT04605289 - Levels of Matrix Metalloproteinase-8 After Intrapocket Treatment in Moderate Periodontitis Patients. | Biotech Hunter | Biotech Hunter