RCT Comparing ESPB Solutions in Breast Surgery

The liposomal bupivacaine used in the research study has been approved by the U.S. Food and Drug Administration (FDA) for use in humans for pain management. The specific approved uses are postsurgical single-dose wound infiltration analgesia and brachial plexus nerve block. In this study, we will be using liposomal bupivacaine in an additional way by infiltrating liposomal bupivacaine in a tissue plane to numb the nerves that provide sensation over the chest.

The medications that are typically administered as a solution in this block include bupivacaine, epinephrine, dexamethasone, and clonidine.