TACE Combined With Lenvatinib and Sintilimab for Advanced HCC

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2020

Primary Completion Date

November 29, 2021

Study Completion Date

October 31, 2022

Conditions
Hepatocellular Carcinoma Non-resectable
Interventions
DRUG

TACE combined with lenvatinib and sintilimab

Lenvatinib 12mg (body weight ≥60kg) or 8mg (body weight \<60kg) P.O. qd and sintilimab 200mg I.V. q3w will be started at 3-7 days after the first TACE.TACE will be repeated if clinically indicated. Treatment of sintilimab will last up to 24 months. Patients will be allowed to have lenvatilib or sintilimab as a sigle agent and will be still considered on study when the other drug cause intolerable toxicity.

Trial Locations (1)

510260

The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou

All Listed Sponsors
lead

Second Affiliated Hospital of Guangzhou Medical University

OTHER

NCT04599790 - TACE Combined With Lenvatinib and Sintilimab for Advanced HCC | Biotech Hunter | Biotech Hunter