TACE Combined With Sorafenib and Tislelizumab for Advanced HCC

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2020

Primary Completion Date

October 11, 2022

Study Completion Date

October 11, 2022

Conditions
Hepatocellular Carcinoma Non-resectable
Interventions
DRUG

TACE combined with sorafenib and tislelizumab

Sorafenib (400mg P.O. Bid) and tislelizumab (200mg I.V. q3w) will be started at 3-7 days after the first TACE. TACE will be repeated if clinically indicated. Treatment of tislelizumab will last up to 24 months. Patients will be allowed to have sorafenib or tislelizumab as a sigle agent and will be still considered on study when the other drug cause intolerable toxicity.

Trial Locations (2)

510260

The 2nd Affiliated Hospital of Guangzhou Medical University, Guangzhou

the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou

All Listed Sponsors
lead

Second Affiliated Hospital of Guangzhou Medical University

OTHER

NCT04599777 - TACE Combined With Sorafenib and Tislelizumab for Advanced HCC | Biotech Hunter | Biotech Hunter