NCT04598633View on ClinicalTrials.gov

Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment

NAUnknownINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

November 24, 2020

Primary Completion Date

December 1, 2022

Study Completion Date

December 1, 2022

Conditions
GingivitisOrthodontic Appliance Complication
Interventions
DIETARY_SUPPLEMENT

Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289)

Supplementary intake of Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289) 2 times per day for 12 weeks

DIETARY_SUPPLEMENT

Placebo-lozenges (BioGaia)

Placebo-lozenges (BioGaia) 2 times per day for 12 weeks

Trial Locations (1)

91054

RECRUITING

UniversityHospitalErlangen-Nurenberg, Erlangen

Sponsors

Collaborators (1)

BioGaia AB
All Listed Sponsors
collaborator

BioGaia AB

INDUSTRY

lead

University of Erlangen-Nürnberg

OTHER

NCT04598633 - Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment | Biotech Hunter | Biotech Hunter