Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia

NACompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

September 1, 2017

Primary Completion Date

March 31, 2018

Study Completion Date

March 31, 2018

Conditions
Multiple System Atrophy, Cerebellar Variant (Disorder)Spinocerebellar Ataxias
Interventions
DEVICE

Cerebellar repetitive transcranial magnetic stimulation

rTMS was delivered on the scalp for over 2 cm under the inion, which is the scalp over the cerebellum area, using a double-cone coil connected to a Magstim Rapid2® stimulator with two Booster Modules (Magstim, Spring Gardens, Wales, UK) in accordance with safety recommendations. Stimulation was delivered to the cerebellum at 10 Hz with 90% of the mean resting motor threshold intensity for 5 seconds at 55 second intervals to deliver 1000 pulses in 20 minutes. Immediately after rTMS, the combination treatment group received balance and gait training by a physical therapist for 30 minutes/day and underwent aerobic exercise using a stationary bicycle at moderate intensity (12 to 14 rating of perceived exertion) for 30 minutes/day and 5 days/week for two weeks. In the control group, no participants received physical therapy or rTMS for two weeks.

Trial Locations (1)

Unknown

Samsung Medical Center, Seoul

All Listed Sponsors
lead

Samsung Medical Center

OTHER

NCT04595578 - Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia | Biotech Hunter | Biotech Hunter