30
Participants
Start Date
June 15, 2022
Primary Completion Date
July 24, 2024
Study Completion Date
July 31, 2024
Active LIFUP Treatment
Low intensity focused ultrasound pulsation will be administered to the internal globus pallidus in 20 sonications at 650kHz, ispta.3 720mW/cm, pulse repetition frequency 100Hz, duty cycle 5%, duration 30s with 30s spacing between sonications. For active LIFUP, the device will be used with a gel pad that allows the ultrasound to pass through.
Sham LIFUP Treatment
The device will be aimed at the internal globus pallidus and turned on with the same settings as the active condition; however, in this case, the device will be used with a gel pad that blocks the ultrasound from passing through, such that no ultrasound is actually being administered to the brain.
University of California, Los Angeles, Los Angeles
University of California, Los Angeles
OTHER