Effect of Automated Closed-Loop Ventilation Versus Conventional Ventilation on Duration and Quality of Ventilation

NARecruitingINTERVENTIONAL
Enrollment

1,200

Participants

Timeline

Start Date

October 19, 2020

Primary Completion Date

March 1, 2025

Study Completion Date

June 30, 2025

Conditions
Ventilator-free DaysQuality of Breathing
Interventions
PROCEDURE

INTELLiVENT-ASV

INTELLiVENT-ASV is activated as soon possible. The sensors for ETCO2 and SpO2 are connected and activated. Patient's gender and height are set on the ventilator and patient condition is chosen if applicable.

PROCEDURE

CONVENTIONAL VENTILATION

Conventional ventilation consists of VCV or PCV and PSV, depending on patient's activity. None of the semi or fully automated modes of ventilation is allowed at any time.

Trial Locations (10)

Unknown

NOT_YET_RECRUITING

Ospedale Policlinico San Martino, Genoa

NOT_YET_RECRUITING

Policlinico San Matteo Fondazione IRCCS, Pavia

NOT_YET_RECRUITING

Flevoziekenhuis, Almere Stad

RECRUITING

Academic Medical Center, Intensive Care, Amsterdam

RECRUITING

Reinier de Graaf Gasthuis, Delft

NOT_YET_RECRUITING

Catharina Ziekenhuis, Eindhoven

NOT_YET_RECRUITING

Leiden UMC, Leiden

NOT_YET_RECRUITING

Canisius-Wilhelmina Hospital, Nijmegen

NOT_YET_RECRUITING

Elisabeth-TweeSteden Ziekenhuis, Tilburg

NOT_YET_RECRUITING

Diakonessenhuis, Utrecht, Utrecht

All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

collaborator

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER

collaborator

Catharina Ziekenhuis Eindhoven

OTHER

collaborator

Reinier de Graaf Groep

OTHER

collaborator

Flevoziekenhuis

OTHER

collaborator

Leiden University Medical Center

OTHER

collaborator

Canisius-Wilhelmina Hospital

OTHER

collaborator

Elisabeth-TweeSteden Ziekenhuis

OTHER

collaborator

Diakonessenhuis, Utrecht

OTHER

collaborator

Ospedale Policlinico San Martino

OTHER

collaborator

Fondazione IRCCS Policlinico San Matteo di Pavia

OTHER

lead

Prof. Dr. Marcus J. Schultz

OTHER