Safety and Efficacy of XmAb18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

4

Participants

Timeline

Start Date

May 10, 2021

Primary Completion Date

March 24, 2022

Study Completion Date

March 24, 2022

Conditions
Merkel Cell CarcinomaSmall Cell Lung Cancer
Interventions
BIOLOGICAL

XmAb18087

Monoclonal bispecific antibody

DRUG

XmAb18087 ± Pembrolizumab

XmAb18087 ± Pembrolizumab

Trial Locations (7)

10065

Memorial Sloan Kettering, New York

73104

OU Health, Stephenson Cancer Center, Oklahoma City

90033

USC/Norris Comprehensive Cancer Center, Los Angeles

91010

City of Hope, Duarte

98109

Swedish Cancer Institute, Seattle

University of Washington, Seattle

03756

Dartmouth Hitchcock Medical Center, Lebanon

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

ICON plc

INDUSTRY

lead

Xencor, Inc.

INDUSTRY