Metabolism Informed Smoking Treatment: The MIST RCT

PHASE3CompletedINTERVENTIONAL
Enrollment

606

Participants

Timeline

Start Date

November 17, 2020

Primary Completion Date

May 20, 2024

Study Completion Date

November 22, 2024

Conditions
Smoking
Interventions
BEHAVIORAL

Post-discharge automated phone calls (IVR) with option to connect with a tobacco coach.

Automated calls to assess smoking status, medication use, and additional support for quit attempt.

DRUG

Nicotine Replacement Therapy

FDA-approved forms of nicotine replacement therapy for smoking cessation.

DRUG

Varenicline

FDA-approved smoking cessation medication.

OTHER

Metabolism Informed Smoking Treatment (Nicotine metabolite ratio (NMR)-based selection of pharmacotherapy)

Nicotine metabolite ratio (NMR)-based selection of pharmacotherapy. NMR is a blood test to measure how fast the body breaks down nicotine.

Trial Locations (1)

37203

Vanderbilt University Medical Center ViTAL, Vanderbilt Center for Tobacco, Addiction, and Lifestyle General Internal Medicine and Public Health 2525 West End Ave, Suite 450, Nashville

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

National Institutes of Health (NIH)

NIH

lead

Vanderbilt-Ingram Cancer Center

OTHER

NCT04590404 - Metabolism Informed Smoking Treatment: The MIST RCT | Biotech Hunter | Biotech Hunter