NCT04589611View on ClinicalTrials.gov

Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

July 20, 2022

Primary Completion Date

December 1, 2023

Study Completion Date

December 1, 2023

Conditions
OsteoarthritisPost-traumatic Osteoarthritis
Interventions
DRUG

amobarbital/Gel-One (one dose)

One dose of amobarbital/Gel-One during the initial surgical intervention

DRUG

Placebo (single dose)

One dose of placebo during the initial surgical intervention

DRUG

amobarbital/Gel-One (two doses)

One dose of amobarbital/Gel-One during the initial surgical intervention. A second dose will be administered during the second surgical intervention.

DRUG

Placebo (two doses)

One dose of placebo during the initial surgical intervention. A second dose will be administered during the second surgical intervention.

Trial Locations (1)

52240

University of Iowa, Iowa City

All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

J L Marsh

OTHER