Inorganic Nitrate: Sex Differences in Muscle Contractile Function and Efficiency

PHASE1CompletedINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

January 20, 2020

Primary Completion Date

December 30, 2023

Study Completion Date

December 30, 2023

Conditions
Healthy
Interventions
DRUG

concentrated beet root juice

On average, we will expect subjects to ingest the supplement for approximately 5 days minimum depending on their testing schedule. On each testing day subjects will be asked to consume the two bottles of either beetroot juice (BRJ) or Placebo 2.5 hours before testing time. Specifically, for female subjects, they will be asked to start their supplementation on day 1 of menses. On day 3-4 they will take the last 2 shots. Female subjects' wash-out period will go according to their menstrual cycle as we will be controlling for hormone fluctuation (low vs high estrogen phase) know to interact with nitric oxide physiology.

DRUG

Placebo beet root juice

This will follow the same supplementation regime as explained above but this supplement taste and looks exactly the same as the nitrate-rich beet root juice. It is provided by the same company that produces the concentrated beet root juice shots (Beet It, UK)

Trial Locations (1)

22903

University of Virginia, Charlottesville

All Listed Sponsors
lead

University of Virginia

OTHER

NCT04588740 - Inorganic Nitrate: Sex Differences in Muscle Contractile Function and Efficiency | Biotech Hunter | Biotech Hunter