214
Participants
Start Date
October 23, 2020
Primary Completion Date
September 13, 2021
Study Completion Date
September 13, 2021
Placebo
Risankizumab placebo will be given at an equal volume at the same schedule.
Remdesivir
Remdesivir is a single diastereomer monophosphoramidate prodrug for the intracellular delivery of a modified adenine nucleoside analog GS-441524.
Risankizumab
Risankizumab is a humanized immunoglobulin (Ig) G1 antagonistic monoclonal antibody (mAb) directed against the p19 subunit of the human cytokine interleukin-23. Risankizumab is formulated in a buffer of 4.4 mM disodium succinate hexahydrate/succinic acid, 225 mM sorbitol, 0.2 mg/mL polysorbate 20, and WFI in a 6R vial.
Nuvance Health - Vassar Brothers Medical Center, Poughkeepsie
The State University of New York - University at Buffalo - Department of Medicine, Buffalo
Doylestown Hospital, Doylestown
West Virginia University - Infectious Diseases Clinic, Morgantown
Wake Forest Baptist Health - Infectious Diseases, Winston-Salem
Grady Memorial Hospital, Atlanta
University of Toledo Medical Center - Ruppert Clinic, Toledo
Hennepin Healthcare Research Institute, Minneapolis
Monument Health - Clinical Research, Rapid City
Cook County Health and Hospitals System - Ruth M Rothstein CORE Center, Chicago
Rush University Medical Center, Chicago
University of Nebraska Medical Center- Infectious Diseases, Omaha
Baptist Hospitals of Southeast Texas Site, Beaumont
Hendrick Health - Hendrick Medical Center, Abilene
St. Anthony Hospital North Health Campus, Westminster
Penrose Hospital - Emergency Medicine, Colorado Springs
St. Francis Medical Center, Colorado Springs
Hoag Hospital Newport Beach, Newport Beach
The University of Arizona - Banner University Medical Center Tucson Campus - Tucson, Tucson
Kern Medical Center, Bakersfield
Stanford University - Stanford Hospital and Clinics - Pediatrics - Infectious Diseases, Stanford
St. Anthony Hospital, Lakewood
Nuvance Health Danbury Hospital - Infectious Disease, Danbury
Yale School of Medicine - The Anlyan Center for Medical Research & Education - Immunobiology, New Haven
Nuvance Health - Norwalk Hospital - Asthma Pulmonary and Critical Care Medicine, Norwalk
Emory Vaccine Center - The Hope Clinic, Decatur
Brigham and Women's Hospital - Infectious Diseases, Boston
Boston Medical Center - Center for Infectious Diseases - Shapiro Center, Boston
Englewood Hospital, Englewood
Mount Sinai School of Medicine - Medicine - Infectious Diseases, New York
Jacobi Medical Center, The Bronx
Kent County Memorial Hospital, Warwick
National Institute of Allergy and Infectious Diseases (NIAID)
NIH