Safety and Immunogenicity of an MF59-Adjuvanted Influenza Vaccine in Older Adults

PHASE2CompletedINTERVENTIONAL
Enrollment

471

Participants

Timeline

Start Date

October 8, 2020

Primary Completion Date

March 19, 2021

Study Completion Date

May 24, 2021

Conditions
InfluenzaHuman
Interventions
BIOLOGICAL

Investigational aIIV4c

Investigational MF59 Adjuvanted Cell-derived Quadrivalent Influenza vaccine, containing four influenza virus strains (A/H1N1, A/H3N2, B/Yamagata and Victoria lineage) recommended by the WHO (World Health Organization) for quadrivalent vaccines for the respective season.

BIOLOGICAL

IIV4c

Licensed, Non-adjuvanted, Cell-derived Quadrivalent Influenza Vaccine containing four influenza virus strains (A/H1N1, A/H3N2, B/Yamagata and Victoria lineage) recommended by the WHO for quadrivalent vaccines for the respective season.

BIOLOGICAL

aIIV4

Licensed, MF59-Adjuvanted, egg-derived Quadrivalent Influenza Vaccine containing four influenza virus strains (A/H1N1, A/H3N2, B/Yamagata and Victoria lineage) recommended by the WHO for quadrivalent vaccines for the respective season.

BIOLOGICAL

RIV4

Licensed, Recombinant Quadrivalent Influenza Vaccine containing four influenza virus strains (A/H1N1, A/H3N2, B/Yamagata and Victoria lineage) recommended by the WHO for quadrivalent vaccines for the respective season.

Trial Locations (21)

13901

4007 - Regional Clinical Research / United Medical Associates, Binghamton

27612

4012 - M3 Wake Research, Inc., Raleigh

32205

4006 - Westside Center for Clinical Research, Jacksonville

32216

4013 - Jacksonville Center for Clinical Research, Jacksonville

33334

4021 - Research Centers of America, LLC, Oakland

36608

4022 - Coastal Clinical Research, an AMR company, Mobile

40509

4001 - Central Kentucky Research Associates, an AMR company, Lexington

44122

4017 - Rapid Medical Research, Inc., Cleveland

45219

4004 - Sterling research, Cincinnati

63141

4024 - Sundance Clinical Research, LLC, St Louis

64114

4008 - The Center for Pharmaceutical Research, an AMR company, Kansas City

67114

4010 - Heartland Research Associates, LLC, Newton

67207

4016 - Heartland Research Associates, LLC - An AMR Company, Wichita

68134

4009 - Meridian Clinical Research, LLC, Omaha

70065

4014 - Medpharmi, Kenner

73112

4011 - Lynn Health Science Institute, Oklahoma City

77375

4018 - Martin Diagnostic Clinic, Tomball

78229

4005 - Clinical Trials of Texas, Inc., San Antonio

83642

4023 - Advanced Clinical Research, Boise

84088

4020 - Advanced Clinical Research, West Jordan

85283

4002 - Clinical Research Consortium, an AMR company, Tempe

All Listed Sponsors
lead

Seqirus

INDUSTRY

NCT04576702 - Safety and Immunogenicity of an MF59-Adjuvanted Influenza Vaccine in Older Adults | Biotech Hunter | Biotech Hunter