A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York

Memorial Sloan Kettering Cancer Center, New York

New York Medical College, Valhalla

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park

Albany Medical Center, Albany

State University of New York Upstate Medical University, Syracuse

Roswell Park Cancer Institute, Buffalo

Children's Hospital of Pittsburgh of UPMC, Pittsburgh

Children's Hospital of Philadelphia, Philadelphia

Saint Christopher's Hospital for Children, Philadelphia

Alfred I duPont Hospital for Children, Wilmington

Children's National Medical Center, Washington D.C.

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore

VCU Massey Comprehensive Cancer Center, Richmond

Children's Hospital of The King's Daughters, Norfolk

West Virginia University Healthcare, Morgantown

Wake Forest University Health Sciences, Winston-Salem

Duke University Medical Center, Durham

East Carolina University, Greenville

Carolinas Medical Center/Levine Cancer Institute, Charlotte

Prisma Health Richland Hospital, Columbia

BI-LO Charities Children's Cancer Center, Greenville

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta

Nemours Children's Clinic-Jacksonville, Jacksonville

University of Florida Health Science Center - Gainesville, Gainesville

Arnold Palmer Hospital for Children, Orlando

Nemours Children's Hospital, Orlando

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa

Johns Hopkins All Children's Hospital, St. Petersburg

Golisano Children's Hospital of Southwest Florida, Fort Myers

Children's Hospital of Alabama, Birmingham

Vanderbilt University/Ingram Cancer Center, Nashville

East Tennessee Childrens Hospital, Knoxville

University of Mississippi Medical Center, Jackson

Norton Children's Hospital, Louisville

Nationwide Children's Hospital, Columbus

Children's Hospital Medical Center of Akron, Akron

Cincinnati Children's Hospital Medical Center, Cincinnati

Dayton Children's Hospital, Dayton

Riley Hospital for Children, Indianapolis

Ascension Saint Vincent Indianapolis Hospital, Indianapolis

Corewell Health Children's, Royal Oak

C S Mott Children's Hospital, Ann Arbor

Children's Hospital of Michigan, Detroit

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids

University of Iowa/Holden Comprehensive Cancer Center, Iowa City

Children's Hospital of Wisconsin, Milwaukee

University of Wisconsin Carbone Cancer Center - University Hospital, Madison

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis

University of Minnesota/Masonic Cancer Center, Minneapolis

Mayo Clinic in Rochester, Rochester

Sanford Broadway Medical Center, Fargo

Lurie Children's Hospital-Chicago, Chicago

University of Illinois, Chicago

University of Chicago Comprehensive Cancer Center, Chicago

Cardinal Glennon Children's Medical Center, St Louis

Washington University School of Medicine, St Louis

Children's Mercy Hospitals and Clinics, Kansas City

Children's Hospital and Medical Center of Omaha, Omaha

University of Nebraska Medical Center, Omaha

Children's Hospital New Orleans, New Orleans

University of Oklahoma Health Sciences Center, Oklahoma City

UT Southwestern/Simmons Cancer Center-Dallas, Dallas

Cook Children's Medical Center, Fort Worth

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston

M D Anderson Cancer Center, Houston

Children's Hospital of San Antonio, San Antonio

University of Texas Health Science Center at San Antonio, San Antonio

Dell Children's Medical Center of Central Texas, Austin

Children's Hospital Colorado, Aurora

Saint Luke's Cancer Institute - Boise, Boise

Primary Children's Hospital, Salt Lake City

University of New Mexico Cancer Center, Albuquerque

Children's Hospital Los Angeles, Los Angeles

Loma Linda University Medical Center, Loma Linda

Children's Hospital of Orange County, Orange

Lucile Packard Children's Hospital Stanford University, Palo Alto

Kaiser Permanente-Oakland, Oakland

Oregon Health and Science University, Portland

Seattle Children's Hospital, Seattle

Madigan Army Medical Center, Tacoma

Providence Sacred Heart Medical Center and Children's Hospital, Spokane

Arkansas Children's Hospital, Little Rock

Connecticut Children's Medical Center, Hartford

Yale University, New Haven

Maine Children's Cancer Program, Scarborough

Walter Reed National Military Medical Center, Bethesda

Dana-Farber Cancer Institute, Boston

Morristown Medical Center, Morristown

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick

University of Alberta Hospital, Edmonton

British Columbia Children's Hospital, Vancouver

CancerCare Manitoba, Winnipeg

IWK Health Centre, Halifax

Children's Hospital of Eastern Ontario, Ottawa

Hospital for Sick Children, Toronto

The Montreal Children's Hospital of the MUHC, Montreal

Centre Hospitalier Universitaire Sainte-Justine, Montreal

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke

CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec