Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19

NACompletedINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

August 19, 2020

Primary Completion Date

December 1, 2020

Study Completion Date

December 1, 2020

Conditions
Pneumonia, ViralCovid19ARDSOxidative Stress
Interventions
DRUG

Vitamin C

Vitamin C. Tablet of 1 gr. A dose of 1 gr every 12 hours. Dissolve one tablet in a volume of 30 ml of water and administer it immediately, then rinse the glass with 10 ml of water and administer it to the patient. Protect from light at all times, as it is photosensitive.

DRUG

Vitamin E

Vitamin E. 800 mg tablet. 800 mg dose every 24 hours. Dissolve the capsule in 30 ml of hot water. The administration of vitamin E is recommended during or after meals since its absorption depends on pancreatic enzymes' presence.

DRUG

Melatonin

"Melatonin Tablet 5 mg. A dose of 50 mg every 24 hours. Grind the 10 5 mg melatonin tablets (50 mg), levitate with 50 mL of Ora-plus (Transferring to a beaker with a magnetic stirrer). Maintain gentle agitation. Rinse the mortar with 10 mL of Ora-sweet. Add 30 mL of Ora sweet to the glass where the mixture is being made. Makeup with Ora-sweet cbp 100 mL Place label FL02 with legend Melatonin 50 mg / 20 mL. Protected from light (Dispense in a black bag that covers the transparent bag of the preparation)'s primary packaging) Give after breakfast."

DRUG

N-acetyl cysteine

N-acetylcysteine. Tablets, 600 mg. 600 mg dose every 12 hours. Dissolve one tablet in a volume of 30 ml of water and administer it immediately, then rinse the glass with 10 ml of water and administer it to the patient.

DRUG

Pentoxifylline

Pentoxifylline. 400 mg tablets. 400 mg dose every 12 hours. The tablet is dissolved in 30 ml of water and is administered orally or nasogastric tube.

Trial Locations (1)

11200

Unidad Temporal COVID-19 en Centro Citibanamex, Mexico City

All Listed Sponsors
collaborator

Instituto Nacional de Cardiologia Ignacio Chavez

OTHER

collaborator

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

OTHER

lead

Unidad Temporal COVID-19 en Centro Citibanamex

OTHER

NCT04570254 - Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19 | Biotech Hunter | Biotech Hunter