Deferoxamine In the Treatment of Aneurysmal Subarachnoid Hemorrhage (aSAH)

PHASE2RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

March 20, 2022

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Aneurysmal Subarachnoid Hemorrhage
Interventions
DRUG

Deferoxamine

"There will be 3 doses given to the patients days 1-3. Dose will be given intravenous with a fixed rate of 7.5 milligram per kilogram per hour (mg/kg/hr). The second dose will be given 24 hours after the first dose, and the third dose will be given 48 hours after the initial dose.~Patients will be randomized to 32 mg/kg or 48 mg/kg of Deferoxamine."

DRUG

Placebo

There will be 3 doses given to the patients days 1-3. Dose will be given intravenous with a fixed rate of 7.5 mg/kg/hr. The second dose will be given 24 hours after the first dose, and the third dose will be given 48 hours after the initial dose.

Trial Locations (2)

48109

RECRUITING

University of Michigan, Ann Arbor

Unknown

NOT_YET_RECRUITING

Peking University Health Science Center, Beijing

All Listed Sponsors
collaborator

Michigan Medicine PKUHSC Joint Institute for Translational & Clinical Research

UNKNOWN

lead

Aditya S. Pandey, MD

OTHER