Effect of Genetic Alterations Affecting the Genes Encoding the Major Enzymes of the Kynurenine Pathway on Suicidal Behavior

CompletedOBSERVATIONAL
Enrollment

849

Participants

Timeline

Start Date

December 1, 2019

Primary Completion Date

March 1, 2023

Study Completion Date

March 1, 2023

Conditions
Tryptophan Metabolism AlterationsPolymorphismSuicidal Behavior
Interventions
GENETIC

SNP (single nucleotide polymorphism) genotyping

"We use TaqMan technique to perform SNP genotyping. The PCR reactions are carried out using the Roche Light Cycler 480 thermal cycler following the protocol recommended by Thermo Fisher Scientific. Then, replication of 10% of the samples is carried out."

Trial Locations (2)

28049

José-Fernandez-Piqueras, Madrid

30029

Department of Psychiatry, Nimes University Hospital, Nîmes

All Listed Sponsors
collaborator

Universidad Autonoma de Madrid

OTHER

lead

Centre Hospitalier Universitaire de Nīmes

OTHER

NCT04565834 - Effect of Genetic Alterations Affecting the Genes Encoding the Major Enzymes of the Kynurenine Pathway on Suicidal Behavior | Biotech Hunter | Biotech Hunter