NCT04562558View on ClinicalTrials.gov

Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

NAActive, not recruitingINTERVENTIONAL
Enrollment

228

Participants

Timeline

Start Date

September 29, 2020

Primary Completion Date

November 11, 2024

Study Completion Date

December 31, 2025

Conditions
Gestational Trophoblastic TumorGestational Trophoblastic NeoplasiaStage I Gestational Trophoblastic TumorStage II Gestational Trophoblastic TumorStage III Gestational Trophoblastic TumorInvasive MoleChoriocarcinoma
Interventions
DRUG

Methotrexate

50mg intramuscularly on Days 1, 3, 5, 7 . Repeat every 14 days

DRUG

Leucovorin

15mg intramuscularly on Days 2, 4, 6, 8. Repeat every 14 days

DRUG

Dactinomycin

1.25mg/m2 (2mg max dose)intravenous every 14 days.

Trial Locations (1)

100730

Peking Union Medical College Hospital, Beijing

All Listed Sponsors
lead

xiang yang

OTHER