Aquablation vs. Holmium Laser Enucleation of the Prostate in the Treatment of Benign Prostatic Hyperplasia in Medium to Large Size Prostates

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 5, 2021

Primary Completion Date

April 30, 2023

Study Completion Date

November 30, 2027

Conditions
Benign Prostatic Hyperplasia (BPH)
Interventions
PROCEDURE

Aquablation

"By means of a high-pressure saline stream, parenchymal tissue of the prostate is removed endoscopically through a heat-free mechanism called hydrodissection. The intervention is supported by live ultrasound guidance and the required depth as well as the angle of the resection is planned out prior to the resection. The bladder is accessed using a 24-Fr hand-piece, which accommodates the scope. The handpiece is supported by an articulating arm attached to the operation table. Once placed in the optimal position, the system automatically adjusts the alignment as necessary.~Hemostasis is consecutively achieved through diathermy and post procedure, a threeway catheter is inserted and bladder irrigation is initiated."

PROCEDURE

HoLEP

This is done endoscopically under general anesthesia the three lobes of the prostate that are cored out intact with the laser are pushed into the bladder before being morcellated by a special instrument inserted through the telescopic camera. A catheter is placed into the bladder to drain the urine while the raw surface heals, then left in place for around 24 hours before being removed on the day of discharge from hospital. Sterile saline fluid is also irrigated into the bladder through the catheter to dilute any blood in the urine and prevent clots from forming.

Trial Locations (1)

9010

RECRUITING

Cantonal Hospital St. Gallen, Sankt Gallen

All Listed Sponsors
lead

Dr. med. Gautier Müllhaupt

OTHER