Diastolic Performance and Norepinephrine in Spinal-Induced Hypotension for Cesarean Delivery

CompletedOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

January 14, 2020

Primary Completion Date

December 15, 2020

Study Completion Date

December 15, 2020

Conditions
Hypotension
Interventions
DRUG

Norepinephrine

Norepinephrine is administered as a continuous infusion at 0.05 mcg/kg/min and is kept to maintain systolic blood pressure within 90-120% of baseline during spinal anaesthesia. The infusion is started at the same time cerebrospinal fluid is obtained, immediately before injection of spinal medications, through a small-bore tubing connected directly to the peripheral intravenous catheter. It is stopped 5 minutes

DEVICE

ClearSight®, Edwards Lifescience, Irvine, CA

"All patients are connected to a ClearSight® monitor (ClearSight®, Edwards Lifescience, Irvine, CA) by an inflatable finger cuff placed on the midphalanx of hand middle or ring finger with no radial artery catheter and its heart reference system (HRS) is zeroed at the level of the patient's midaxillary line.~The ClearSight® monitoring is started in the pre-anaesthesia room and calibrated for 5 minutes before recording. The monitoring continues throughout the procedure until patient transfer in the recovery room. All data are anonymously collected on a USB pen for statistical analysis."

Trial Locations (1)

00168

IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome

All Listed Sponsors
lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

NCT04560634 - Diastolic Performance and Norepinephrine in Spinal-Induced Hypotension for Cesarean Delivery | Biotech Hunter | Biotech Hunter